Antibiotic sensitivity profile of uropathogenic Escherichia coli strains at the China-Guinea Friendship Hospital of Kipé in Conakry (Guinea)

Introduction: Escherichia coli (E. coli) is one of the main bacterial species associated with urinary tract infections. Nowadays, this bacterium becoming more and resistant to antibiotics. Objective: The aim study was determine antibiotic sensitivity profiles all strains E. isolated from urine during period September 1st, 2018 March 13th, 2019 at Biomedical Laboratory China-Guinea Friendship Hospital Kipé in Conakry. Materiel Methods: Cultures were done on different agar media. Bacterial identification, antibiograms determination minimum inhibitory concentrations (MIC) performed Vitek 2 Compact 15 automated system. Results: A total 66 have been patients both sexes. sex ratio (M/F) 0.43. mean age 50.83 years. majority sensitive imipenem (96.96%), amikacin ertapenem (94.73%), gentamicin (69.23%), tobramycin (60, 60%), cefoxitin (64.28%), cefotaxime (62.50%), piperacillin/tazobactam (77.4%), amoxicillin/clavulanic acid (50.00%) nitrofurantoin (87%). In contrast, ampicillin (81.81%), cefalotin (62.02%), ticarcillin (88.00%), nalidixic (82.75%), ciprofloxacin (56.06%), ofloxacin (56.00%) combination trimethoprim/sulfamethoxazole (83.60%), sometimes high MICs. Conclusion: Our results show that infections due are frequently observed females than males. Some these studied exhibited multidrug resistance Among classes antibiotics tested, carbapenemes, nitrofurans, aminoglycosides, appear be active uropathogenes Guinea.